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Interventional Radiology & Image-Guided Therapy

The interventional radiology research team consists of a diverse group of scientists and physicians who strive to develop novel minimally invasive image-guided therapies. A major focus of this group is in the Interventional Oncology space and the development of novel drug delivery systems. Through collaboration with colleagues in areas across the Feinberg School of Medicine and Northwestern University (including medical oncology, transplant surgery, hepatology, vascular surgery, biomedical engineering and molecular biology), our research interests have recently included development of novel drug delivery systems using nanotechnology approaches, techniques for catheter-based embolization of tumors, novel ablation strategies and device development.

 Kush Desai

My primary research and clinical interests are in venous thromboembolic disease, including IVC filter management/complex IVC filter retrieval, deep venous thrombolysis, reconstruction of chronic venous occlusions, and interventional pulmonary embolism management.

For more information on my research, please view my Feinberg School of Medicine faculty profile.

Publications

View my publications on Northwestern Scholars.

 Dong-Hyun Kim

Image-guided medicine is rapidly growing to improve treatment regimens and advancing medical imaging, including magnetic resonance imaging (MRI), computed tomography (CT), radiography, ultrasound, positron emission tomography (PET), and single photon emission computed tomography (SPECT). A combination of modern nanoplatforms with high performance in imaging and therapeutics may be critical to improve medical outcomes.

One of emerging fields is image-guided therapy using various nanoparticles. Therapies include basic bench, preclinical in vitro/in vivo and clinical researches combining synthesis of multifunctional nanoparticle and tracking/navigation tools to improve accuracy and outcomes of the therapeutics. Most of the emerging interventional technique such as heat-activated targeted drug delivery, image guided ablation (microwave or HIFU), percutaneous injection gene/bacteria therapy, transcatheter treatments for tumor specific local therapy, serial biopsy, thrombolytic therapy, and so on, can be combined with nanotechnology in clinic.

My research engages in careful design/selection/synthesis of multifunctional imaging/therapeutic nanomaterials with therapeutic agents will be critical for the translational optimization these new image guided medicine techniques. The DHKIM Lab for Biomaterials​ of Image Guided NanoMedicine has focused on developing various therapeutic/imaging carriers for the treatment of various cancers. Micro/Nanoparticles and their hybrid derivatives have been exploited as vectors for drug/therapeutic delivery and molecular imaging agents of MRI, CT, ultrasound and luminescent/fluorescents. We are working closely with clinicians, medical scientists, biologist and imaging professionals to translate new therapeutic approaches using multifunctional carriers and diagnostic imaging technique to the clinical setting.

Lab Manager: Xiaoke Huang

For more information on my research, please view my Feinberg School of Medicine faculty profile.

Publications

View my publications on Northwestern Scholars.

 Robert Lewandowski

I am primarily interested in loco-regional therapies to treat primary and secondary liver cancersm, I am involved in both pre-clinical and clinical studies along these lines. My most recent research involves utilizing image-guided Y-90 radioembolization in HCC resection. I am also very interested in the use of IVC filters in patients with venous thromboembolic disease.

For more information on my research, please view my Feinberg School of Medicine faculty profile.

Publications

View my publications on Northwestern Scholars.

 Samdeep Mouli

Dr. Mouli's lab uses imaging in the treatment of solid organ malignancies including primary and metastatic liver cancer, pancreatic cancer, and prostate cancer. His interests include translational research focused on the application of novel minimally invasive image-guided therapies for cancer treatment, as well as the development of novel drug delivery systems.

For more information on my research, please view my Feinberg School of Medicine faculty profile.

Publications

View my publications on Northwestern Scholars.

 Ahsun Riaz

My research and clinical interests focus on advancing the field of Interventional Radiology.

For more information on my research, please view my Feinberg School of Medicine faculty profile.

Publications

View my publications on Northwestern Scholars.

 Riad Salem

I am the Vice Chair for Image Guided Therapy, Department of Radiology and Chief of Vascular Interventional Radiology in the Department of Radiology. As a Professor of Radiology, Medicine (Hematology and Oncology) and Surgery (Organ Transplantation) at Northwestern Memorial Hospital who specializes in interventional oncology, my research focuses considerably on international oncology. I have collaborated in many pre-clinical and clinical research projects and published regularly on preclinical studies including the PDAC mouse, rat, and VX2 pancreatic tumor model, ablation procedures, and MRI.

For more information on my research, please view my Feinberg School of Medicine faculty profile.

Publications

View my publications on Northwestern Scholars.

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