TRIOG Director

Contact

Northwestern University Feinberg School of Medicine
Department of Radiology
737 N. Michigan Ave, 16th Floor, Chicago, IL 60611
phone: (312)926-3499 fax: (312)926-5991
a-larson@northwestern.edu

Education

• Ph.D. Northwestern University 2004
• M.S. Northwestern University 2002
• B.S. Marquette University 1999

Employment

• Northwestern University Department of Radiology
  Assistant Professor of Radiology 2005-present
  Instructor of Radiology 2004-2005
• Northwestern University Department of Biomedical Engineering
  Assistant Professor (affiliated faculty) 2005-present
• Northwestern University Department of Electrical Engineering and Computer Science
  Professor (courtesy appointment) 2005-present
• NIH NHLBI Laboratory of Cardiac Energetics
  Pre-IRTA Fellow Medical Imaging Section 2002-2004

Research Interests

• Interventional MRI for the optimization, guidance, and monitoring of minimally invasive liver-directed therapies (TACE, Y-90 radioembolization).
• Functional MRI (BOLD, DWI, DCE) for the staging of hepatocarcinogensis and detection and/or early prediction of therapy response.
• Technical development of rapid MRI techniques for temporally constrained imaging applications (non-Cartesian sampling, parallel imaging, steady-state pulse sequences).

Professional Organizations and Affiliations

• Robert H. Lurie Comprehensive Cancer Center (associate member)
• International Society of Magnetic Resonance in Medicine
• Society of Interventional Radiology

Selected Publications

1. Larson AC, Wang D, Atassi B, Sato KT, Ryu RK, Lewandowski RJ, Nemcek Jr A, Mulcahy MF, Kulik L, Miller FH, Salem R, Omary RA. Transcatheter intraarterial perfusion (TRIP) – MRI monitoring of chemoembolization for hepatocellular carcinoma: feasibility of initial clinical translation. Radiology 2008 (in press)
2. Deng J, Omary R, Larson A. Multi-shot diffusion-Weighted SPLICE PROPELLER MRI of the abdomen. Magn Reson Med 2008 (in press).
3. Deng J, Virmani S, Young J, Harris K, Yang G, Rademaker A, Woloschak G, Omary RA, Larson AC. Diffusion-weighted PROPELLER MRI for quantitative assessment of liver tumor necrotic fraction and viable tumor volume in VX2 rabbits. J Magn Reson Imag (in press) 2008.
4. Wang D, Bangash AK, Rhee TK, Woloschak GE, Paunesku T, Salem R, Omary RA, Larson AC. Liver tumors: monitoring embolization in VX2 rabbits with transcatheter intraarterial first-pass perfusion MR imaging. Radiology 2007 245(1):130-139.
5. Wang D, Bangash A, Rhee T, Woloschak GE, Paunesku T, Salem R, Omary RA, Larson AC. Transcatheter intraarterial first-pass perfusion (TRIP) – MRI monitoring of liver tumor embolization in VX2 rabbits. Radiology 2007 Oct; 245(1):130-9.
6. Deng J, Miller FH, Salem R, Omary RA, Larson AC. Multi-shot diffusion-weighted PROPELLER MRI of the abdomen. Investigative Radiology 2006 41(10):769-75
7. Deng J, Miller FH, Rhee TK, Sato KT, Mulcahy MF, Kulik LM, Salem R, Omary RA, Larson AC. Diffusion-weighted MRI for determination of hepatocellular carcinoma response to Yttrium-90 radioembolization. J Vasc Interv Radiol 2006 17:1195-1200
8. Larson AC, Rhee TK, Deng J, Wang D, Sato KT, Salem R, Paunesku T, Li D, Omary RA. Comparison between intravenous and intraarterial contrast injection for dynamic 3D MRI of liver tumors in VX2 rabbit model. J Magn Reson Imag 2006 24(1):242-7
9. Deng J, Rhee TK, Salem R, Haines K, Paunesku T, Mulcahy MF, Miller FH, Omary RA, Larson AC. In vivo diffusion weighted imaging of liver tumor necrosis in the VX2 rabbit model at 1.5 Tesla. Investigative Radiology 2006 41(4):410-4